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(S, R, S) -AHPC-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH

This compound, VH032-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH, is a VHL-targeting ligand-linker conjugate used in PROTAC development. It facilitates the recruitment of E3 ubiquitin ligase machinery for targeted protein degradation, a strategy widely applied in both in vitro and in vivo cancer and disease biology research.

Product Specifications

CAS Number

2086301-47-3

Field of Research

Musculoskeletal & Connective Tissue Research, Pharmacology & Drug Discovery

Smiles

C[C@H] (NC (=O) [C@@H]1C[C@@H] (O) CN1C (=O) [C@@H] (NC (=O) CN1CCC (CC1) O[C@H]1C[C@@H] (C1) NC (=O) OC (C) (C) C) C (C) (C) C) c1ccc (cc1) -c1scnc1C

Molecular Formula

C39H58N6O7S

Molecular Weight

754.99

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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