RIP2 Kinase Inhibitor 4
RIP2 Kinase Inhibitor 4 is a potent and selective RIPK2 PROTAC degrader (pIC50 = 8) that suppresses TNF-α release. This compound is a valuable tool for studying NOD signaling in inflammatory and autoimmune disease research, applicable in both cellular and in vivo models.
Product Specifications
CAS Number
2126803-41-4
Field of Research
Cell Biology, Pharmacology & Drug Discovery, Signal Transduction
Smiles
CN[C@@H] (C) C (=O) N[C@H] (C (=O) N1C[C@H] (C[C@H]1C (=O) Nc1c (F) cccc1F) NC (=O) c1cnc (cn1) N1CCN (CCCOc2cc3ncnc (Nc4n[nH]c (C) c4C) c3cc2S (=O) (=O) C (C) (C) C) CC1) C (C) (C) C |@@:70|
Molecular Formula
C50H66F2N14O7S
Molecular Weight
1045.23
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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