Ziftomenib
Ziftomenib (KO-539) is a potent and selective small molecule inhibitor of the menin-MLL protein interaction. It is used in leukemia research, demonstrating antitumor efficacy in both cellular assays and in vivo models of MLL-rearranged and NPM1-mutant acute myeloid leukemia.
Product Specifications
CAS Number
2134675-36-6
Product Name Alternative
Menin-MLL, Histone Methyltransferase, HistoneMethyltransferase, KO539, KO-539, KO 539, Ziftomenib
Field of Research
Epigenetics & Chromatin
Purity
98.30% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (4.6 mM) ; DMSO:80 mg/mL (111.44 mM)
Smiles
CNc1nc (NC2CCN (Cc3ccc4n (C[C@H] (C) N5CCN (CC5) S (C) (=O) =O) c (cc4c3C) C#N) CC2) c2cc (CC (F) (F) F) sc2n1
Molecular Formula
C33H42F3N9O2S2
Molecular Weight
717.871
Storage Conditions
-20°C
Notes
For research use only.
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