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(R) -GSK-3685032

(R) -GSK-3685032 is the R-enantiomer of a potent, selective, reversible, and non-covalent DNMT1 inhibitor (IC50 = 36 nM) . This first-in-class compound induces DNA demethylation, reactivates gene transcription, and inhibits cancer cell proliferation, making it a valuable tool for epigenetic research in oncology, both in vitro and in vivo.

Product Specifications

CAS Number

2170140-50-6

Field of Research

Epigenetics & Chromatin

Smiles

CCc1c (C#N) c (S[C@@H] (C (N) =O) c2ccccc2) nc (N2CCC (N) CC2) c1C#N

Molecular Formula

C22H24N6OS

Molecular Weight

420.54

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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