CCR4 antagonist 3
CCR4 antagonist 3 is a potent, selective, and orally bioavailable small molecule inhibitor of CCR4, featuring a novel piperidinyl-azetidine scaffold. It demonstrates nanomolar potency in calcium flux and chemotaxis assays and exhibits antitumor activity in research models, supporting its use in oncology and immunology research.
Product Specifications
CAS Number
2174938-70-4
Field of Research
Immunology & Inflammation, Immunology & Inflammation; Pharmacology & Drug Discovery, Infectious Disease & Virology, Pharmacology & Drug Discovery
Smiles
[H][C@@]1 (CCCN (CCO) C1) C1CN (C1) c1cnc2c (nn ([C@H] (C) c3ccc (Cl) cc3Cl) c2n1) C#N
Molecular Formula
C24H27Cl2N7O
Molecular Weight
500.43
Storage Conditions
-20°C
Notes
For research use only.
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