CCR4 antagonist 3 hydrochloride
CCR4 antagonist 3 hydrochloride is a potent, selective, and orally bioavailable small molecule inhibitor of CCR4, featuring a novel piperidinyl-azetidine scaffold. It demonstrates inhibitory activity in calcium flux (IC50=22 nM) and chemotaxis assays, supporting its use in oncology research for investigating CCR4-mediated pathways in vitro and in vivo.
Product Specifications
CAS Number
2174938-71-5
Field of Research
Immunology & Inflammation, Immunology & Inflammation; Pharmacology & Drug Discovery, Infectious Disease & Virology, Pharmacology & Drug Discovery
Smiles
[C@H] (C) (N1C=2C (C (C#N) =N1) =NC=C (N2) N3CC (C3) [C@@H]4CN (CCO) CCC4) C5=C (Cl) C=C (Cl) C=C5.Cl
Molecular Formula
C24H27Cl2N7O.xHCl
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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