Ethaselen
Ethaselen (BBSKE) is an orally bioavailable, selective inhibitor of thioredoxin reductase 1 (TrxR1) . It demonstrates anticancer activity by inducing apoptosis and inhibiting proliferation, particularly in colorectal cancer models, and shows synergistic effects when combined with oxaliplatin in both in vitro and in vivo studies.
Product Specifications
CAS Number
217798-39-5
Product Name Alternative
BBSKE, TrxR
Field of Research
Metabolism Research
Purity
97.58% (May vary between batches)
Solubility
10% DMSO+90% Corn Oil:1 mg/mL (2.37 mM) ; DMSO:10 mg/mL (23.69 mM)
Smiles
O=C1C=2C=CC=CC2[Se]N1CCN3[Se]C=4C=CC=CC4C3=O
Molecular Formula
C16H12N2O2Se2
Molecular Weight
422.2
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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