CM121
CM121 is a potent, reversible, and active-site directed inhibitor of ALDH1A2, with an IC50 of 0.54 μM and a Kd of 1.1 μM, mediated by hydrophobic interactions. This small molecule is a valuable chemical probe for studying retinoic acid biosynthesis in cancer stem cell biology and developmental research, applicable in both in vitro and in vivo models.
Product Specifications
CAS Number
2204230-40-8
Field of Research
Metabolism Research
Smiles
CS (=O) (=O) c1ccc (cc1) -c1nn (cc1C (=O) Nc1cccc (F) c1) -c1ccc (cc1) C#N
Molecular Formula
C24H17FN4O3S
Molecular Weight
460.48
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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