BCR-ABL-IN-3
BCR-ABL-IN-3 is a potent, irreversible Bcr-Abl inhibitor with an IC50 of ≤100 nM against the T315I mutant in Ba/F3 cells. It demonstrates significant anti-cancer activity and is a valuable tool for investigating resistance mechanisms in chronic myeloid leukemia research, both in vitro and in vivo.
Product Specifications
CAS Number
2240191-12-0
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Smiles
O[C@@H]1CCN (C1) c1ncc (cc1-c1cnsc1) C (=O) Nc1ccc (OC (F) (F) Cl) cc1
Molecular Formula
C20H17ClF2N4O3S
Molecular Weight
466.89
Storage Conditions
-20°C
Notes
For research use only.
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