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AHR antagonist 5 free base

This orally bioavailable small molecule is a potent AHR antagonist, demonstrating IC50 values of 35-150 nM across human and rodent cell lines. Its anticancer activity supports its use in vitro and in vivo for researching oncology, immunology, and toxicology pathways.

Product Specifications

CAS Number

2247950-42-9

Product Name Alternative

AHR antagonist 5, AHR antagonist 5 free base, ArylHydrocarbonReceptor, Aryl Hydrocarbon Receptor, aryl hydrocarbon receptor

Field of Research

Immunology & Inflammation, Pharmacology & Drug Discovery

Purity

99.29% (May vary between batches)

Solubility

DMSO:50 mg/mL (113.25 mM) ;10% DMSO+90% Corn Oil:2.5 mg/mL (5.66 mM)

Smiles

N (C=1N2C (=C (C (C) C) C=N2) N=C (N1) C=3C=C (F) C=NC3) [C@H]4CC=5C=6C (NC5CC4) =CC=CC6

Molecular Formula

C25H24FN7

Molecular Weight

441.5

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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