AHR agonist 3
AHR agonist 3 is an aryl hydrocarbon receptor (AhR) agonist, that can induces cell cycle arrest or apoptosis via activation of tumor-suppressive transcriptional programs. AHR agonist 3 inhibits triple-negative breast cancer (TNBC) stem cell growth via AhR while exhibits minimal cytotoxicity against normal human primary cells and can be used for cancer research[1].
Product Specifications
CAS Number
[23749-58-8]
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Apoptosis; Aryl Hydrocarbon Receptor
Type
Reference compound
Related Pathways
Apoptosis; Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ahr-agonist-3.html
Purity
99.79
Solubility
DMSO : 10 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
C1=CC=C2C(=C1)N=C3C4=CC=CC5=C4C(=CC=C5)C(=O)N23
Molecular Formula
C18H10N2O
Molecular Weight
270.28
Precautions
H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
IFI44 (Interferon-induced Protein 44, p44, Microtubule-associated Protein 44, MTAP44)
NR4A3 (Nuclear Receptor Subfamily 4, Group A, Member 3, CHN, CSMF, MINOR, NOR1, TEC) (MaxLight 550)
NR4A3 (Nuclear Receptor Subfamily 4, Group A, Member 3, CHN, CSMF, MINOR, NOR1, TEC) (MaxLight 550)