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PROTAC ERRα Degrader-3

PROTAC ERRα Degrader-3 is a potent and selective VHL-based degrader of ERRα, achieving >80% degradation at 30 nM with no off-target activity against ERRβ/γ. This tool compound is valuable for investigating ERRα's role in cancer, metabolism, and bone biology in both cellular and in vivo models.

Product Specifications

CAS Number

2306388-65-6

Field of Research

Metabolism Research, Pharmacology & Drug Discovery

Smiles

COc1cc (\C=C (/C#N) C (=O) NCCCCC (=O) N[C@H] (C (=O) N2C[C@H] (O) C[C@H]2C (=O) NCc2ccc (cc2) -c2scnc2C) C (C) (C) C) ccc1OCc1ccc (cc1C (F) (F) F) C (F) (F) F

Molecular Formula

C47H50F6N6O7S

Molecular Weight

957.0

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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