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SR-717 free acid

SR-717 free acid is a stable, non-nucleotide STING agonist that functions as a cGAMP mimetic. It demonstrates potent antitumor activity in vitro, with EC50 values of approximately 2.1-2.2 μM in both wild-type and cGAS knockout reporter cell lines, supporting its use in immuno-oncology research.

Product Specifications

CAS Number

2375420-34-9

Field of Research

Immunology & Inflammation

Smiles

OC (=O) c1cc (F) c (F) cc1NC (=O) c1ccc (nn1) -n1ccnc1

Molecular Formula

C15H9F2N5O3

Molecular Weight

345.266

Storage Conditions

-20°C

Notes

For research use only.

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