M-1211
M 1121 is a potent, orally bioavailable small molecule inhibitor that disrupts the menin-MLL protein-protein interaction. It demonstrates robust anti-tumor activity in preclinical models, achieving complete and durable regression in vivo, and is a key research tool for studying MLL-rearranged leukemias.
Product Specifications
CAS Number
2377337-93-2
Field of Research
Epigenetics & Chromatin
Smiles
[H][C@]12CN ([C@] ([H]) (CN1C (=O) C=C) C2) S (=O) (=O) c1ccc (cc1) N1CC (CN2CCC (CC2) [C@@] (CN2CCC2) (c2cccc (F) c2) [C@@]2 ([H]) CCC[C@@H]2NC (=O) OC) (C1) OC |@@:29, TLB:13:3:12:7.6, THB:8:7:12:3.2|
Molecular Formula
C42H57FN6O6S
Molecular Weight
793.01
Storage Conditions
-20°C
Notes
For research use only.
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