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M-1211

M 1121 is a potent, orally bioavailable small molecule inhibitor that disrupts the menin-MLL protein-protein interaction. It demonstrates robust anti-tumor activity in preclinical models, achieving complete and durable regression in vivo, and is a key research tool for studying MLL-rearranged leukemias.

Product Specifications

CAS Number

2377337-93-2

Field of Research

Epigenetics & Chromatin

Smiles

[H][C@]12CN ([C@] ([H]) (CN1C (=O) C=C) C2) S (=O) (=O) c1ccc (cc1) N1CC (CN2CCC (CC2) [C@@] (CN2CCC2) (c2cccc (F) c2) [C@@]2 ([H]) CCC[C@@H]2NC (=O) OC) (C1) OC |@@:29, TLB:13:3:12:7.6, THB:8:7:12:3.2|

Molecular Formula

C42H57FN6O6S

Molecular Weight

793.01

Storage Conditions

-20°C

Notes

For research use only.

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