AU-15330
AU-15330 is a PROTAC molecule that induces the degradation of SMARCA4, SMARCA2, and PBRM1. It demonstrates selective cytotoxicity in H3.3K27M-mutant cells in vitro, making it a candidate for research in oncology, particularly for studying chromatin remodeling complexes in diffuse midline glioma models.
Product Specifications
CAS Number
2380274-50-8
Product Name Alternative
AU15330, AU-15330, AU 15330, EpigeneticReaderDomain, Epigenetic Reader Domain, PROTAC
Field of Research
Epigenetics & Chromatin, Pharmacology & Drug Discovery
Purity
98.21% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (6.61 mM) ; DMSO:252.5 mg/mL (334.03 mM)
Smiles
C[C@H] (NC (=O) [C@@H]1C[C@@H] (O) CN1C (=O) [C@@H] (NC (=O) CN1CCN (CC1) c1cc (nnc1N) -c1ccccc1O) C (C) (C) C) c1ccc (cc1) -c1scnc1C
Molecular Formula
C39H49N9O5S
Molecular Weight
755.93
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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