AU-15330
AU-15330 is a PROTAC molecule that induces the degradation of SMARCA4, SMARCA2, and PBRM1. It demonstrates selective cytotoxicity in H3.3K27M-mutant cells in vitro, making it a candidate for research in oncology, particularly for studying chromatin remodeling complexes in diffuse midline glioma models.
Product Specifications
CAS Number
2380274-50-8
Product Name Alternative
AU15330, AU-15330, AU 15330, EpigeneticReaderDomain, Epigenetic Reader Domain, PROTAC
Field of Research
Epigenetics & Chromatin, Pharmacology & Drug Discovery
Purity
98.21% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (6.61 mM) ; DMSO:252.5 mg/mL (334.03 mM)
Smiles
C[C@H] (NC (=O) [C@@H]1C[C@@H] (O) CN1C (=O) [C@@H] (NC (=O) CN1CCN (CC1) c1cc (nnc1N) -c1ccccc1O) C (C) (C) C) c1ccc (cc1) -c1scnc1C
Molecular Formula
C39H49N9O5S
Molecular Weight
755.93
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Recombinant Xenopus laevis Protein FAM168B (fam168b)
Recombinant Xenopus laevis Protein FAM168B (fam168b)