JNJ-67569762
JNJ-67569762 is a potent and selective BACE1 inhibitor with an IC50 of 2.7 nM, targeting the enzyme's S3 subsite. This small molecule is a valuable research tool for investigating BACE1 function in Alzheimer's disease pathogenesis, applicable in both in vitro enzymatic assays and in vivo model studies.
Product Specifications
CAS Number
2380313-26-6
Field of Research
Neuroscience
Smiles
CCS (=O) (=O) [C@]1 (C) CC[C@] (CF) (N=C1N) c1cc (NC (=O) c2cc3OC (F) (F) Oc3cn2) ccc1F |c:12|
Molecular Formula
C22H22F4N4O5S
Molecular Weight
530.49
Storage Conditions
-20°C
Notes
For research use only.
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