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JNJ-67569762

JNJ-67569762 is a potent and selective BACE1 inhibitor with an IC50 of 2.7 nM, targeting the enzyme's S3 subsite. This small molecule is a valuable research tool for investigating BACE1 function in Alzheimer's disease pathogenesis, applicable in both in vitro enzymatic assays and in vivo model studies.

Product Specifications

CAS Number

2380313-26-6

Field of Research

Neuroscience

Smiles

CCS (=O) (=O) [C@]1 (C) CC[C@] (CF) (N=C1N) c1cc (NC (=O) c2cc3OC (F) (F) Oc3cn2) ccc1F |c:12|

Molecular Formula

C22H22F4N4O5S

Molecular Weight

530.49

Storage Conditions

-20°C

Notes

For research use only.

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