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PKM2-IN-3

PKM2-IN-3 is a potent and selective inhibitor of pyruvate kinase M2 (PKM2) with an IC50 of 4.1 μM. It suppresses glycolytic flux and NLRP3 inflammasome activation, providing a valuable tool for studying neuroinflammation and metabolic reprogramming in both cellular and animal models of neurological disorders.

Product Specifications

CAS Number

2408841-19-8

Field of Research

Metabolism Research

Smiles

CCc1ccc (\C=C2/CCOc3cc (OC) cc (OC) c3C2=O) cc1

Molecular Formula

C21H22O4

Molecular Weight

338.403

Storage Conditions

-20°C

Notes

For research use only.

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