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6'-GNTI dihydrochloride

6'-GNTI dihydrochloride is a G-protein-biased κ-opioid receptor (KOR) agonist that selectively activates the Akt pathway in striatal neurons. This compound is a valuable research tool for investigating biased KOR signaling in vitro and studying neuropsychiatric disorders, including addiction and depression, in preclinical models.

Product Specifications

CAS Number

2410327-94-3

Product Name Alternative

OpioidReceptor, Opioid Receptor, 6'-GNTI, 6'GNTI dihydrochloride, 6'-GNTI Dihydrochloride, 6' GNTI dihydrochloride, Akt, κ-opioid receptor

Field of Research

Metabolism Research, Neuroscience, Pharmacology & Drug Discovery, Signal Transduction

Purity

97.57% (May vary between batches)

Solubility

DMSO:10.42 mg/mL (19.14 mM)

Smiles

O[C@]12[C@]34[C@] (OC5=C (O) C=CC (C[C@@]2 ([H]) N (CC4) CC6CC6) =C53) ([H]) C7=C (C8=CC=C (NC (N) =N) C=C8N7) C1.Cl.Cl

Molecular Formula

C27H29N5O3.2ClH

Molecular Weight

544.47

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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