Pomalidomide-PEG3-CO2H
Pomalidomide-PEG3-CO2H is a cereblon ligand-linker conjugate used in PROTAC development. This compound, featuring a thalidomide derivative and a triethylene glycol spacer, is a key intermediate for constructing heterobifunctional degraders for targeted protein degradation research in both cellular and preclinical models.
Product Specifications
CAS Number
2138440-82-9
Product Name Alternative
Thalidomide-NH-PEG3-propionic acid, E3 Ligase LigandLinker Conjugate, E3 Ligase Ligand-Linker Conjugate, E3LigaseLigandLinkerConjugate, Pomalidomide-PEG3-CO2H
Field of Research
Cell Biology, Pharmacology & Drug Discovery, Pharmacology & Drug Discovery; Cell Biology
Purity
99.05% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (8.38 mM) ; DMSO:100 mg/mL (209.44 mM)
Smiles
O=C1C=2C (C (=O) N1C3C (=O) NC (=O) CC3) =CC=CC2NCCOCCOCCOCCC (O) =O
Molecular Formula
C22H27N3O9
Molecular Weight
477.46
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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