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TLR8 agonist 2 hydrochloride

TLR8 agonist 2 hydrochloride is a potent and selective human TLR8 activator (EC50 = 3 nM) with significantly weaker activity against TLR7 (EC50 = 33.33 μM) . This small molecule is a valuable research tool for studying TLR8-mediated immune signaling in vitro and has been utilized in investigations of antiviral and antitumor responses.

Product Specifications

CAS Number

2412937-65-4

Field of Research

Immunology & Inflammation, Immunology & Inflammation; Pharmacology & Drug Discovery

Smiles

N ([C@@] (CC=1NC=NN1) (CCCC) C) C=2C3=C (N=C (N) N2) C=NC=C3.Cl

Molecular Formula

C16H22N8.xHCl

Storage Conditions

-20°C

Notes

For research use only.

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