S65487 sulfate
S65487 (VOB560) sulfate is a potent, selective Bcl-2 inhibitor active against mutations like G101V and D103Y, with minimal affinity for MCL-1, BFL-1, and BCL-XL. It induces apoptosis and demonstrates anticancer activity in research models, applicable for studying hematological malignancies in both in vitro and in vivo experimental settings.
Product Specifications
CAS Number
2416937-01-2
Field of Research
Cell Biology
Smiles
OS (O) (=O) =O.Cc1c (cc (C#N) n1C) N (C (=O) c1cc (-c2cc (Cl) ccc2C (=O) N2Cc3ccccc3C[C@H]2CN2CCOCC2) n (C) c1C) c1ccc (O) cc1
Molecular Formula
C41H43ClN6O8S
Molecular Weight
815.34
Storage Conditions
-20°C
Notes
For research use only.
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