ATR-IN-9
ATR-IN-9 is a potent and selective ATR kinase inhibitor with an IC50 of 10 nM. It is a valuable chemical probe for studying DNA damage response pathways in cancer research, demonstrating utility in both in vitro cellular assays and in vivo xenograft models to investigate chemosensitization and synthetic lethality.
Product Specifications
CAS Number
2417513-43-8
Field of Research
Epigenetics & Chromatin, Molecular Biology, Signal Transduction
Smiles
C[C@@H]1COCCN1c1cc (c2cnn (-c3cc[nH]n3) c2n1) C1 (O) CCC (C) (CC1) C#N
Molecular Formula
C22H27N7O2
Molecular Weight
421.505
Storage Conditions
-20°C
Notes
For research use only.
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