Sinbaglustat
Sinbaglustat (OGT2378) is an orally bioavailable, brain-penetrant N-alkyl iminosugar functioning as a dual inhibitor of glucosylceramide synthase (GCS) and non-lysosomal glucosylceramidase (GBA2) . It is a research tool for investigating lysosomal storage disorders like Gaucher disease and related neurodegenerative pathologies in both cellular and animal models.
Product Specifications
CAS Number
441061-33-2
Product Name Alternative
Glucosylceramide synthase, OGT 2378, OGT2378, OGT-2378, ACT519276, ACT-519276, ACT 519276, Sinbaglustat
Field of Research
Metabolism Research
Purity
99.93% (May vary between batches)
Solubility
DMSO:46.66 mg/mL (200 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (21.43 mM)
Smiles
CCCCCN1C[C@H] (O) [C@@H] (O) [C@H] (O) [C@@H]1CO
Molecular Formula
C11H23NO4
Molecular Weight
233.3
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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