BACE, Asp2 (CT) (Memapsin2, Beta-site APP Cleaving Enzyme, Aspartyl Protease 2)
Product Specifications
NCBI Gene ID
23621
Reactivity
Human
Storage Conditions
-20 °C
Specificity
Recognizes human beta amyloid cleaving enzyme (BACE), a 70kD aspartic protease. BACE is involved in the cleavage of the amyloid precursor protein (APP) to generate amyloid beta peptide. Cerebral deposition of amyloid beta peptide is an early feature of Alzheimer's disease.
Other Gene Names
[BACE1; BACE1; ASP2; BACE; HSPC104; BACE; KIAA1149; ASP2; Asp 2]
Short Name
[BACE, Asp2]
Other Product Names
[beta-secretase 1 isoform D preproprotein; Beta-secretase 1; beta-secretase 1; asp 2; memapsin-2; APP beta-secretase; aspartyl protease 2; beta-site APP cleaving enzyme 1; beta-secretase 1 precursor variant 1; transmembrane aspartic proteinase Asp2; membrane-associated aspartic protease 2; beta-site amyloid beta A4 precursor protein-cleaving enzyme; beta-site APP-cleaving enzyme 1; Aspartyl protease 2; ASP2; Asp 2; Beta-site amyloid precursor protein cleaving enzyme 1; Beta-site APP cleaving enzyme 1; Memapsin-2; Membrane-associated aspartic protease 2]
NCBI GI Number
21040368
NCBI Accession Number
NP_620429.1
NCBI GB Accession Number
NM_138973.3
Uniprot Accession Number
P56817
Available Sizes
Curated Selection
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