BACE, Asp2 (CT) (Memapsin2, Beta-site APP Cleaving Enzyme, Aspartyl Protease 2)

Recognizes human beta amyloid cleaving enzyme (BACE), a 70kD aspartic protease. BACE is involved in the cleavage of the amyloid precursor protein (APP) to generate amyloid beta peptide. Cerebral deposition of amyloid beta peptide is an early feature of Alzheimer's disease.

[beta-secretase 1 isoform D preproprotein; Beta-secretase 1; beta-secretase 1; asp 2; memapsin-2; APP beta-secretase; aspartyl protease 2; beta-site APP cleaving enzyme 1; beta-secretase 1 precursor variant 1; transmembrane aspartic proteinase Asp2; membrane-associated aspartic protease 2; beta-site amyloid beta A4 precursor protein-cleaving enzyme; beta-site APP-cleaving enzyme 1; Aspartyl protease 2; ASP2; Asp 2; Beta-site amyloid precursor protein cleaving enzyme 1; Beta-site APP cleaving enzyme 1; Memapsin-2; Membrane-associated aspartic protease 2]