NO2-SPDB-sulfo
NO2-SPDB-sulfo is a cleavable, sulfonated linker used in the synthesis of antibody-drug conjugates (ADCs) for targeted cancer therapy. Its disulfide bridge enables controlled drug release in the reducing intracellular environment, which is critical for both in vitro cytotoxicity assays and in vivo efficacy studies of ADC candidates.
Product Specifications
CAS Number
663598-89-8
Smiles
OS (=O) (=O) C1CC (=O) N (OC (=O) CCCSSc2ccc (cn2) N (=O) =O) C1=O
Molecular Formula
C13H13N3O9S3
Molecular Weight
451.44
Storage Conditions
-20°C
Notes
For research use only.
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