NSC 23766
NSC 23766 is a selective Rac1 GTPase inhibitor that blocks Rac1 activation via specific GEF interaction without affecting Cdc42 or RhoA. It is widely used in cancer and cardiovascular research, demonstrating dose-dependent anti-proliferative effects in vitro and modulating endothelial function and platelet activity in experimental models.
Product Specifications
CAS Number
733767-34-5
Product Name Alternative
NSC 23766, NSC23766, NSC-23766
Field of Research
Cell Biology, Neuroscience, Pharmacology & Drug Discovery, Signal Transduction
Purity
99.49% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween-80+45% Saline:3.3 mg/mL (7.83 mM) ; DMSO:80 mg/mL (189.76 mM)
Smiles
N=1C (=NC (=CC1NC=2C=CC=3N=C (C=C (N) C3C2) C) C) NC (C) CCCN (CC) CC
Molecular Formula
C24H35N7
Molecular Weight
421.58
Storage Conditions
-20°C
Notes
For research use only.
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