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Estrogen receptor modulator 6

Compound 3a is a potent and selective ERβ agonist, demonstrating a high binding affinity (K i = 0.44 nM) and 19-fold selectivity over ERα. This tool compound is valuable for investigating ERβ-specific signaling in cellular assays and animal models relevant to inflammation, neuroprotection, and metabolic diseases.

Product Specifications

CAS Number

787621-78-7

Field of Research

Metabolism Research

Smiles

[H][C@]12CC (F) (F) C[C@@]1 ([H]) c1cc (O) ccc1O[C@H]2c1ccc (O) cc1

Molecular Formula

C18H16F2O3

Molecular Weight

318.32

Storage Conditions

-20°C

Notes

For research use only.

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