Estrogen receptor modulator 6
Compound 3a is a potent and selective ERβ agonist, demonstrating a high binding affinity (K i = 0.44 nM) and 19-fold selectivity over ERα. This tool compound is valuable for investigating ERβ-specific signaling in cellular assays and animal models relevant to inflammation, neuroprotection, and metabolic diseases.
Product Specifications
CAS Number
787621-78-7
Field of Research
Metabolism Research
Smiles
[H][C@]12CC (F) (F) C[C@@]1 ([H]) c1cc (O) ccc1O[C@H]2c1ccc (O) cc1
Molecular Formula
C18H16F2O3
Molecular Weight
318.32
Storage Conditions
-20°C
Notes
For research use only.
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