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NMDA receptor antagonist 2

NMDA receptor antagonist 2 is a potent, orally bioavailable, and NR2B-selective NMDA receptor antagonist with sub-nanomolar affinity (IC50 = 1.0 nM, Ki = 0.88 nM) . It is a valuable research tool for investigating neuropathic pain and Parkinson's disease mechanisms in both in vitro and in vivo experimental models.

Product Specifications

CAS Number

875898-41-2

Field of Research

Neuroscience, Neuroscience; Pharmacology & Drug Discovery, Pharmacology & Drug Discovery

Smiles

Cc1ccc (Cc2noc (n2) [C@H]2CC[C@@H] (C2) Nc2ncnc3[nH]ncc23) cc1

Molecular Formula

C20H21N7O

Molecular Weight

375.436

Storage Conditions

-20°C

Notes

For research use only.

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