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MRTX849 analog 24

MRTX849 analog 24 is a click chemistry probe derived from the KRAS G12C inhibitor MRTX849. This alkyne-functionalized analogue enables the study of MRTX849's mechanism, supporting target engagement and biodistribution research in both cellular and animal models of KRAS-driven cancers.

Product Specifications

CAS Number

2490716-96-4

Field of Research

Signal Transduction

Smiles

FC (=C) C (=O) N1CCN (C[C@@H]1CC#N) c1nc (OC[C@@H]2CCCN2CCCC#C) nc2CN (CCc12) c1cccc2cccc (Cl) c12

Molecular Formula

C36H39ClFN7O2

Molecular Weight

656.2

Storage Conditions

-20°C

Notes

For research use only.

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