MrgprX2 antagonist-3
MrgprX2 antagonist-3 (E117) is a selective small molecule antagonist of the Mas-related G-protein coupled receptor X2. It is a valuable research tool for studying MrgprX2-mediated responses, including mast cell degranulation, in both in vitro cellular assays and in vivo models of allergic and pseudoallergic cutaneous inflammation.
Product Specifications
CAS Number
2642174-19-2
Product Name Alternative
MrgprX2 antagonist 3, MrgprX2 antagonist3, MrgprX-2 antagonist-3, MrgprX2 antagonist-3
Field of Research
Pharmacology & Drug Discovery
Purity
98.06% (May vary between batches)
Solubility
DMSO:80 mg/mL (237.1 mM) ;10% DMSO+40% PEG300+5% Tween-80+45% Saline:3.3 mg/mL (9.78 mM)
Smiles
C (C=1SC (NC (N (C[C@H] (C) O) CC) =O) =NC1) C2=CC (F) =CC=C2
Molecular Formula
C16H20FN3O2S
Molecular Weight
337.41
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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