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CDK12-IN-5

CDK12-IN-5 is a potent, orally bioavailable inhibitor of CDK12, demonstrating antitumor activity in preclinical studies. It is utilized in research models of breast and ovarian cancers to investigate CDK12's role in transcription and DNA damage response.

Product Specifications

CAS Number

2651200-35-8

Product Name Alternative

CDK12 IN 5, CDK12IN5, CDK-12-IN-5, CDK12-IN-5, CDK12

Field of Research

Cell Biology, Signal Transduction

Purity

99.37% (May vary between batches)

Solubility

DMSO:100 mg/mL (220.09 mM) ;10% DMSO+90% Corn Oil:3.3 mg/mL (7.26 mM)

Smiles

FC=1C=CC=2N=C (NC2C1F) CNC3=NC (=NC4=C (C=NN34) C (F) (F) F) N5CCOCC5

Molecular Formula

C18H15F5N8O

Molecular Weight

454.36

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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