ITK/TRKA-IN-1
ITK/TRKA-IN-1 is a potent dual inhibitor of IL-2-inducible T-cell kinase (ITK) and tropomyosin receptor kinase A (TRKA), exhibiting an IC50 of 1.0 nM against ITK and 96% TRKA inhibition. This compound is a valuable research tool for investigating T-cell signaling and neurotrophin pathways in both cellular and animal models of immunology and oncology.
Product Specifications
CAS Number
2655557-54-1
Field of Research
Signal Transduction
Smiles
[H][C@]12Cc3c (C[C@@]1 (C) C2 (F) F) [nH]nc3-c1nc2cc (C) c (cc2[nH]1) N (C) C (=O) [C@H] (C) N1CCOCC1
Molecular Formula
C25H30F2N6O2
Molecular Weight
484.552
Storage Conditions
-20°C
Notes
For research use only.
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