HPK1-IN-4
HPK1-IN-4 is a potent and selective preclinical inhibitor of hematopoietic progenitor kinase 1 (HPK1/MAP4K1) with an IC50 of 0.061 nM. This tool compound is utilized in immunological research to investigate HPK1's role in T-cell signaling and function, supporting both in vitro cellular assays and in vivo efficacy studies in preclinical cancer immunotherapy models.
Product Specifications
CAS Number
2739844-28-9
Product Name Alternative
MAP4K, HPK1IN4, HPK-1-IN-4, HPK1-IN-4, HPK1, HPK1 IN 4
Field of Research
Signal Transduction
Purity
97.06% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween-80+45% Saline:1 mg/mL (2.3 mM) ; DMSO:90 mg/mL (207.14 mM)
Smiles
COc1cc2CCN (C) Cc2cc1Nc1ncc (C (N) =O) c (Nc2ccccc2CO) n1
Molecular Formula
C23H26N6O3
Molecular Weight
434.49
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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