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JAK2-IN-6

JAK2-IN-6 is a potent and selective aminothiazole-based JAK2 inhibitor (IC50 = 22.86 μg/mL) with antiproliferative effects, showing no activity against JAK1/JAK3. It is a valuable research tool for studying JAK2-driven signaling in pathologies like myeloproliferative neoplasms and for conducting in vitro cellular proliferation assays.

Product Specifications

CAS Number

353512-04-6

Product Name Alternative

JAK2, JAK2IN6, JAK-2-IN-6, JAK2-IN-6, JAK2 IN 6

Field of Research

Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology

Purity

98.00% (May vary between batches)

Solubility

DMSO:55 mg/mL (163.77 mM)

Smiles

Nc1nc (Nc2ccccc2) sc1C (=O) c1ccc (Cl) s1

Molecular Formula

C14H10ClN3OS2

Molecular Weight

335.83

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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