ZNL 02-096
ZNL 02-096 (Pomalidomide-C3-adavosertib) is a potent and selective Wee1 degrader (IC50=3.58 nM) that spares PLK1. It induces Wee1 degradation, DNA damage, G2/M arrest, and apoptosis in MOLT-4 cells in vitro and demonstrates broad anti-proliferative activity across cancer cell lines, supporting its use in oncology and DNA damage response research.
Product Specifications
CAS Number
2414418-49-6
Product Name Alternative
Apoptosis, Wee1, Pomalidomide-C3-adavosertib, ZNL 02-096
Field of Research
Cell Biology, Pharmacology & Drug Discovery
Purity
98.20% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (1.25 mM) ; DMSO:50 mg/mL (62.51 mM)
Smiles
C (C=C) N1N (C=2C (C1=O) =CN=C (NC3=CC=C (C=C3) N4CCN (CCCNC5=C6C (C (=O) N (C6=O) C7C (=O) NC (=O) CC7) =CC=C5) CC4) N2) C=8N=C (C (C) (C) O) C=CC8
Molecular Formula
C42H45N11O6
Molecular Weight
799.88
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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