FC 11
FC 11 is a potent, reversible PROTAC degrader of FAK and its autophosphorylated form (pFAK Y397), with DC50 values in the picomolar range. This tool compound enables the study of FAK function and its role in cancer cell migration, invasion, and proliferation in both in vitro and in vivo research models.
Product Specifications
CAS Number
2271035-37-9
Field of Research
Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction
Smiles
O=C1C=2C (C (=O) N1C3C (=O) NC (=O) CC3) =CC=CC2NCCOCCOCCN4C=C (C (NC5=CC=C (NC=6N=C (NCC7=C (N (S (C) (=O) =O) C) N=CC=C7) C (C (F) (F) F) =CN6) C=C5) =O) N=N4
Molecular Formula
C41H42F3N13O9S
Molecular Weight
949.91
Storage Conditions
-20°C
Notes
For research use only.
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