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FC 11

FC 11 is a potent, reversible PROTAC degrader of FAK and its autophosphorylated form (pFAK Y397), with DC50 values in the picomolar range. This tool compound enables the study of FAK function and its role in cancer cell migration, invasion, and proliferation in both in vitro and in vivo research models.

Product Specifications

CAS Number

2271035-37-9

Field of Research

Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction

Smiles

O=C1C=2C (C (=O) N1C3C (=O) NC (=O) CC3) =CC=CC2NCCOCCOCCN4C=C (C (NC5=CC=C (NC=6N=C (NCC7=C (N (S (C) (=O) =O) C) N=CC=C7) C (C (F) (F) F) =CN6) C=C5) =O) N=N4

Molecular Formula

C41H42F3N13O9S

Molecular Weight

949.91

Storage Conditions

-20°C

Notes

For research use only.

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