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Clocinnamox mesylate

Clocinnamox mesylate is an irreversible, systemically active μ-opioid receptor antagonist with high affinity (apparent Ki values: μ=0.7 nM, δ=1.9 nM, κ=5.7 nM in mice) . It is a valuable research tool for investigating opioid receptor function and mechanisms of antagonism in both in vitro binding assays and in vivo pharmacological studies.

Product Specifications

CAS Number

117332-69-1

Field of Research

Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Smiles

CS (O) (=O) =O.[H][C@@]12Oc3c4c (C[C@@]5 ([H]) N (CC6CC6) CC[C@@]14[C@]5 (CCC2=O) NC (=O) C=Cc1ccc (Cl) cc1) ccc3O |w:30.33, TLB:8:9:22:14.19.20, THB:39:10:22:14.19.20|

Molecular Formula

C30H33ClN2O7S

Molecular Weight

601.11

Storage Conditions

-20°C

Notes

For research use only.

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