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TAPI-1 trifluoroacetate (163847-77-6 (free base) )

TAPI-1 is a cell-permeable inhibitor of ADAM17/TACE, effectively preventing the ectodomain shedding of cytokine receptors and TNF-α. This compound is widely used in vitro to study inflammatory signaling and has been applied in vivo to investigate models of sepsis and rheumatoid arthritis.

Product Specifications

Field of Research

Protein Biochemistry

Purity

98.06% (May vary between batches)

Smiles

OC (=O) C (F) (F) F.CC (C) CC (CC (=O) NO) C (=O) N[C@@H] (Cc1ccc2ccccc2c1) C (=O) N[C@@H] (C) C (=O) NCCN

Molecular Formula

C28H38F3N5O7

Molecular Weight

613.62

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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