TAPI-1 trifluoroacetate (163847-77-6 (free base) )
TAPI-1 is a cell-permeable inhibitor of ADAM17/TACE, effectively preventing the ectodomain shedding of cytokine receptors and TNF-α. This compound is widely used in vitro to study inflammatory signaling and has been applied in vivo to investigate models of sepsis and rheumatoid arthritis.
Product Specifications
Field of Research
Protein Biochemistry
Purity
98.06% (May vary between batches)
Smiles
OC (=O) C (F) (F) F.CC (C) CC (CC (=O) NO) C (=O) N[C@@H] (Cc1ccc2ccccc2c1) C (=O) N[C@@H] (C) C (=O) NCCN
Molecular Formula
C28H38F3N5O7
Molecular Weight
613.62
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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