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Prexasertib mesylate

Prexasertib (LY2606368) is a potent, selective inhibitor of checkpoint kinases CHK1 and CHK2. It induces replication catastrophe and DNA damage in S-phase cells, enhancing the efficacy of conventional therapies in models of acute lymphoblastic leukemia, as demonstrated in both in vitro and in vivo research.

Product Specifications

CAS Number

1234015-55-4

Field of Research

Cell Biology, Molecular Biology

Smiles

N#CC1=NC=C (N=C1) NC2=NNC (=C2) C=3C (OC) =CC=CC3OCCCN.O=S (=O) (O) C

Molecular Formula

C19H23N7O5S

Molecular Weight

461.49

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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