Prexasertib mesylate
Prexasertib (LY2606368) is a potent, selective inhibitor of checkpoint kinases CHK1 and CHK2. It induces replication catastrophe and DNA damage in S-phase cells, enhancing the efficacy of conventional therapies in models of acute lymphoblastic leukemia, as demonstrated in both in vitro and in vivo research.
Product Specifications
CAS Number
1234015-55-4
Field of Research
Cell Biology, Molecular Biology
Smiles
N#CC1=NC=C (N=C1) NC2=NNC (=C2) C=3C (OC) =CC=CC3OCCCN.O=S (=O) (O) C
Molecular Formula
C19H23N7O5S
Molecular Weight
461.49
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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