MS049 2HCl (1502816-23-0 (free base) )
MS049 is a potent and selective small molecule inhibitor of PRMT4 (CARM1) and PRMT6, with IC50 values of 34 nM and 43 nM, respectively. It shows high selectivity over other PRMTs and methyltransferases. This inhibitor is a valuable chemical probe for investigating the roles of these enzymes in cancer, inflammation, and other diseases in both cellular and animal models.
Product Specifications
Product Name Alternative
Histone Methyltransferase, HistoneMethyltransferase, MS049 2HCl (1502816230 (free base) ), MS-049 2HCl (1502816-23-0 (free base) ), MS049 2HCl (1502816-23-0 (free base) ), MS049 2HCl (1502816 23 0 (free base) ), PRMT4, PRMT6
Field of Research
Epigenetics & Chromatin
Purity
99.90% (May vary between batches)
Solubility
DMSO:30 mg/mL (93.38 mM) ; PBS (pH7.2) :10 mg/mL (31.13 mM) ; Ethanol:30 mg/mL (93.38 mM)
Smiles
Cl.Cl.CNCCN1CCC (CC1) OCc2ccccc2
Molecular Formula
C15H26Cl2N2O
Molecular Weight
321.28
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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