1,3,5-Trihydroxy-4-prenylxanthone
This prenylated xanthone is a phosphodiesterase 5 (PDE5) inhibitor (IC50 = 3.0 μM) and also exhibits cholinesterase inhibitory activity. It functions as an anti-inflammatory agent by suppressing LPS-induced NF-κB and AP-1 signaling pathways through interference with IRAK-1 posttranslational modification. This makes it a useful research tool for studying PDE-related, neurochemical, and innate immune signaling processes.
Product Specifications
CAS Number
53377-61-0
Field of Research
Immunology & Inflammation, Metabolism Research, Pharmacology & Drug Discovery
Smiles
C (C=C (C) C) C1=C2C (C (=O) C=3C (O2) =C (O) C=CC3) =C (O) C=C1O
Molecular Formula
C18H16O5
Molecular Weight
312.32
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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