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Smilagenin

Smilagenin is a natural anthocyanin glycoside that acts as an acetylcholinesterase inhibitor (IC50 = 43.29 mg/L) . It exhibits neuroprotective properties by enhancing CREB phosphorylation, increasing GDNF and BDNF expression, and counteracting Aβ-induced neurodegeneration in research models, supporting its study in neuroscience and neuropharmacology.

Product Specifications

CAS Number

126-18-1

Product Name Alternative

PYM 50028, PYM50028, PYM-50028, Cogane, AI344895, AI3-44895, Smilagenin

Field of Research

Epigenetics & Chromatin, Neuroscience, Signal Transduction

Purity

98.00% (May vary between batches)

Solubility

DMSO:< 1 mg/mL (insoluble) ; Ethanol:≥ 8 mg/mL

Smiles

C[C@@H]1[C@]2 (O[C@@]3 ([C@]1 ([C@]4 (C) [C@@] (C3) ([C@]5 ([C@] (CC4) ([C@]6 (C) [C@] (CC5) (C[C@@H] (O) CC6) [H]) [H]) [H]) [H]) [H]) [H]) CC[C@@H] (C) CO2

Molecular Formula

C27H44O3

Molecular Weight

416.64

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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