Acrizanib
Acrizanib (LHA510) is a potent and selective VEGFR-2 tyrosine kinase inhibitor, demonstrating an IC50 of 17.4 nM in cellular assays. It is a valuable research tool for studying angiogenesis and has been utilized in both in vitro and in vivo models of cancer and other pathologies involving VEGF signaling.
Product Specifications
CAS Number
1229453-99-9
Product Name Alternative
LHA 510, LHA510, LHA-510, Acrizanib, VEGFR2
Field of Research
Cardiovascular Research, Signal Transduction
Purity
98.71% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.49 mM) ; DMSO:37.8 mg/mL (84.87 mM)
Smiles
CNCc1cc (Oc2ccc3n (ccc3c2) C (=O) Nc2cc (n (C) n2) C (F) (F) F) ncn1
Molecular Formula
C20H18F3N7O2
Molecular Weight
445.4
Storage Conditions
-20°C
Notes
For research use only.
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