PKC-theta inhibitor
This small molecule is a potent and selective inhibitor of protein kinase C theta (PKC-θ), exhibiting an IC50 of 12 nM. It is a valuable research tool for studying T-cell activation and immune signaling pathways in both cellular and animal models of inflammation and autoimmunity.
Product Specifications
CAS Number
736048-65-0
Product Name Alternative
Inhibit, Inhibitor, Protein kinase C, PKCtheta inhibitor, PKC-theta inhibitor, PKC theta inhibitor, PKC, PKCθ
Field of Research
Epigenetics & Chromatin, Pharmacology & Drug Discovery, Signal Transduction
Purity
98.07% (May vary between batches)
Solubility
DMSO:62.5 mg/mL (137.53 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.4 mM)
Smiles
NCC1CCC (CNc2nc (NCc3ccccc3OC (F) (F) F) ncc2[N+] ([O-]) =O) CC1
Molecular Formula
C20H25F3N6O3
Molecular Weight
454.45
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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